Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 5/20 | 0.49 |
| ▸ | MMP8 | P22894 | 5/20 | 0.49 |
| ▸ | FCER2 | P06734 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 6/20 | 0.48 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | MMP7 | P09237 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763984 | 0.91 | MMP1 (0.55) | MMP1ITGB1ITGA4ITGB7 | |
| SCHEMBL7406067 | 0.90 | ITGB1 (0.61) | ITGB1ITGA4ITGB7MMP8 | |
| SCHEMBL7765671 | 0.89 | MMP1 (0.56) | MMP1ITGB1ITGA4ITGB7MMP9 | |
| SCHEMBL7761865 | 0.88 | L3MBTL1 (0.53) | MMP1ITGB1ITGA4ITGB7MMP8 | |
| SCHEMBL7761903 | 0.88 | ITGB1 (0.52) | MMP1ITGB1ITGA4ITGB7MMP8 | |
| SCHEMBL7762771 | 0.87 | MMP8 (0.51) | MMP1ITGB1ITGA4ITGB7MMP9 | |
| SCHEMBL7765664 | 0.87 | MMP8 (0.51) | MMP1ITGB1ITGA4ITGB7MMP9 | |
| SCHEMBL9229825 | 0.87 | TACR1 (0.54) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7406177 | 0.86 | ITGB1 (0.48) | MMP1ITGB1ITGA4ITGB7MMP8 | |
| SCHEMBL7405239 | 0.86 | ITGB1 (0.50) | MMP1ITGB1ITGA4ITGB7MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6110967-A | USEFUL AS AGENTS FOR PREVENTING AND TREATING METABOLIC OSTEOPATHY SUCH AS OSTEOPOROSIS, HYPERCALCEMIA AND BONE METASTASIS OF CANCER BECAUSE THEY SPECIFICALLY INHIBITS CATHEPSIN L AND ITS FAMILY ENZYMES TO INHIBIT BONE RESORPTION | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0921122-A1 | NOVEL EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-06-09 | — | — | EP | disclosed |