SCHEMBL7403263

SCHEMBL7403263

C=C[CH]c1c(O)ccc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.61
MAPT P10636 10/20 0.53
KMT2A Q03164 7/20 0.53
MEN1 O00255 6/20 0.53
KDM4E B2RXH2 7/20 0.51
L3MBTL1 Q9Y468 5/20 0.51
ALDH1A1 P00352 4/20 0.51
GAA P10253 3/20 0.51
HPGD P15428 2/20 0.51
ATM Q13315 1/20 0.51
RRM1 P23921 1/20 0.51
THRB P10828 3/20 0.50
POLB P06746 3/20 0.50
MPI P34949 2/20 0.50
PTPN22 Q9Y2R2 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL73027 0.84 ERN1 (0.66) ERN1MAPTKMT2AMEN1KDM4E
SCHEMBL30273052 0.84 ERN1 (0.66) ERN1MAPTKMT2AMEN1KDM4E
SCHEMBL7915280 0.79 ERN1 (0.70) ERN1MAPTKMT2AMEN1KDM4E
SCHEMBL7915285 0.79 ERN1 (0.70) ERN1MAPTKMT2AMEN1KDM4E
SCHEMBL11239630 0.77 CYP2A6 (0.50) ERN1MAPTKMT2AMEN1L3MBTL1
Formamide SCHEMBL9731302 0.77 ERN1 (0.66) ERN1MAPTKMT2AMEN1KDM4E
SCHEMBL304032 0.76 ERN1 (1.00) ERN1MAPTKMT2AMEN1KDM4E
SCHEMBL6411521 0.76 ERN1 (0.66) ERN1MAPTKMT2AMEN1KDM4E
SCHEMBL1520145 0.76 ERN1 (0.66) ERN1MAPTKMT2AMEN1KDM4E
SCHEMBL29358409 0.76 ERN1 (1.00) ERN1MAPTKMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0396122-A2 Ambient temperature curable polyorganosiloxanes UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1990-11-07 EP claimed
JP-2308857-A None JP disclosed
WO-1998030590-A9 ANALOGS OF PARATHYROID HORMONE BIOMEASURE INC (US) 1999-08-19 WO disclosed
EP-0772448-A4 CYCLIC ANALOGS OF PTH AND PTHrP BETH ISRAEL HOSPITAL (US) 1999-05-26 EP disclosed
US-5717062-A PARATHYROID HORMONE BETH ISRAEL HOSPITAL ASSOCIATION (US) 1998-02-10 US disclosed
EP-0772448-A1 CYCLIC ANALOGS OF PTH AND PTHrP Beth Israel Deaconess Medical Center, Inc. (US) 1997-05-14 EP disclosed
WO-1996040193-A1 CYCLIC ANALOGS OF PTH AND PTHrP BETH ISRAEL HOSPITAL ASSOCIATION (US) 1996-12-19 WO disclosed
JP-H02308857-A ROOM-TEMPERATURE-CURING POLYORGANOSILOXANE UNION CARBIDE CHEM & PLAST CO INC 1990-12-21 JP disclosed
EP-0396122-A2 Ambient temperature curable polyorganosiloxanes UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1990-11-07 EP disclosed