Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 12/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73027 | 0.91 | ERN1 (0.66) | ERN1KDM4EHTTNPC1KMT2A | |
| SCHEMBL30273052 | 0.91 | ERN1 (0.66) | ERN1KDM4EHTTNPC1KMT2A | |
| Hydrazine SCHEMBL28732767 | 0.80 | ERN1 (0.92) | ERN1KDM4EHTTNPC1KMT2A | |
| Formamide SCHEMBL9731250 | 0.80 | ERN1 (0.45) | ERN1KDM4EHTTNPC1KMT2A | |
| SCHEMBL304032 | 0.80 | ERN1 (1.00) | ERN1KDM4EHTTNPC1KMT2A | |
| SCHEMBL29358409 | 0.80 | ERN1 (1.00) | ERN1KDM4EHTTNPC1KMT2A | |
| SCHEMBL11407376 | 0.78 | ERN1 (0.96) | ERN1KDM4EHTTNPC1KMT2A | |
| SCHEMBL11520332 | 0.78 | ERN1 (0.96) | ERN1KDM4EHTTNPC1KMT2A | |
| SCHEMBL28033846 | 0.78 | ERN1 (0.96) | ERN1KDM4EHTTNPC1KMT2A | |
| Formamide SCHEMBL9730844 | 0.77 | LDHA (0.42) | ERN1KDM4EHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | claimed |
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |