Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368640 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TDP1MAPK8 | |
| SCHEMBL7402170 | 0.85 | KMT2A (0.48) | ALDH1A1MAPK8 | |
| SCHEMBL7365200 | 0.82 | MAPK8 (0.62) | ALDH1A1MAPTMAPK8RAB9AMAPK1 | |
| SCHEMBL7369302 | 0.76 | L3MBTL1 (0.47) | ALDH1A1MAPTRAB9AGALR3MAPK1 | |
| SCHEMBL7367839 | 0.76 | NAPRT (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL7372342 | 0.75 | PDE10A (0.48) | ALDH1A1 | |
| SCHEMBL7677512 | 0.74 | KMT2A (0.53) | ALDH1A1MAPK8RAB9A | |
| SCHEMBL3732870 | 0.73 | PPARA (0.49) | — | |
| SCHEMBL5218853 | 0.73 | ALDH1A1 (0.54) | ALDH1A1TDP1MAPTMAPK8RAB9A | |
| SCHEMBL7694995 | 0.73 | TDP1 (0.55) | ALDH1A1TDP1MAPTMAPK8RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380218-B1 | FOR THERAPY OF RESPIRATORY, ALLERGIC, AND INFLAMMATORY DISORDERS COMPRISING ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ACUTE RESPIRATORY DISEASE SYNDROME, PULMONARY HYPERSENSITIVITY, AND ALLERGIC RHINITIS IN A MAMMAL | PFIZER INC | 2002-04-30 | — | — | US | disclosed |
| EP-0971894-A1 | NICOTINAMIDE DERIVATIVES | Pfizer Products Inc. (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998045268-A1 | NICOTINAMIDE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1998-10-15 | — | — | WO | disclosed |