Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405137 | 0.87 | NR3C1 (0.39) | NR3C1MEN1KMT2APGRNR3C2 | |
| SCHEMBL7403331 | 0.77 | CRHBP (0.48) | NR3C1KCNA5MEN1KMT2A | |
| SCHEMBL11160283 | 0.69 | NR3C1 (0.43) | NR3C1MEN1KMT2APGRNR3C2 | |
| SCHEMBL1612858 | 0.68 | KMT2A (0.53) | NR3C1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6321619 | 0.68 | MEN1 (0.49) | KCNA5ABCB1MEN1KMT2ATDP1 | |
| SCHEMBL6321614 | 0.68 | MEN1 (0.49) | KCNA5ABCB1MEN1KMT2ATDP1 | |
| SCHEMBL25663392 | 0.68 | MEN1 (0.49) | KCNA5ABCB1MEN1KMT2ATDP1 | |
| SCHEMBL5360860 | 0.67 | ADRA2B (0.56) | KCNA5ABCB1MEN1KMT2ANPC1 | |
| SCHEMBL14482225 | 0.67 | EPOR (0.44) | KCNA5ABCB1MEN1KMT2ANPC1 | |
| SCHEMBL14482223 | 0.67 | EPOR (0.44) | KCNA5ABCB1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169181-B1 | HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITORS | PHARMACIA & UPJOHN COMPANY | 2001-01-02 | — | — | US | disclosed |
| EP-0758327-A1 | PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030670-A2 | PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |