Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404767 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1GAAHRH3 | |
| SCHEMBL7994997 | 0.85 | FFAR1 (0.38) | ALDH1A1 | |
| SCHEMBL7393253 | 0.80 | ITGB3 (0.56) | ITGB3ITGA2BALDH1A1GAAHRH3 | |
| SCHEMBL7334455 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BALDH1A1GAAHRH3 | |
| SCHEMBL11566578 | 0.75 | FFAR1 (0.42) | ALDH1A1 | |
| SCHEMBL7395120 | 0.75 | ITGB3 (0.58) | ITGB3ITGA2BALDH1A1GAAHRH3 | |
| SCHEMBL7334548 | 0.75 | ITGB3 (0.62) | ITGB3ITGA2BHRH3 | |
| SCHEMBL23754113 | 0.74 | FFAR1 (0.48) | ALDH1A1 | |
| SCHEMBL7336053 | 0.74 | ITGB3 (0.40) | ITGB3ITGA2BALDH1A1GAAHRH3 | |
| SCHEMBL7403779 | 0.74 | ITGB3 (0.58) | ITGB3ITGA2BALDH1A1GAAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |