Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.54 |
| ▸ | HRH1 | P35367 | 6/20 | 0.47 |
| ▸ | HRH2 | P25021 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634962 | 0.90 | ITGB3 (0.47) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7994992 | 0.85 | LMNA (0.43) | GAA | |
| SCHEMBL9081854 | 0.79 | ITGB3 (0.51) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL9080518 | 0.78 | ITGB3 (0.54) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL7393253 | 0.78 | ITGB3 (0.56) | ITGB3ITGA2BHRH3ALDH1A1GAA | |
| SCHEMBL7334548 | 0.77 | ITGB3 (0.62) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8889083 | 0.76 | ITGB3 (0.50) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8890427 | 0.76 | ITGB3 (0.63) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8635826 | 0.76 | HRH3 (0.54) | ITGB3ITGA2BHRH3HRH1HRH2 | |
| SCHEMBL8890373 | 0.76 | ITGB3 (0.60) | ITGB3ITGA2BHRH3HRH1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | claimed |
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |