Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | TPH1 | P17752 | 4/20 | 0.43 |
| ▸ | TPH2 | Q8IWU9 | 4/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400871 | 0.84 | TPH1 (0.43) | SCARB1GRIN1GRIN2BTPH1TPH2 | |
| SCHEMBL7407177 | 0.80 | F10 (0.64) | F2F10F7 | |
| SCHEMBL7407685 | 0.80 | F10 (0.48) | TPH1TPH2F2F10F7 | |
| SCHEMBL7407680 | 0.78 | F10 (0.49) | TPH1TPH2F2F10F7 | |
| SCHEMBL7405159 | 0.72 | F10 (0.55) | F2F10F7 | |
| SCHEMBL7265526 | 0.70 | GAA (0.69) | GRIN1GRIN2BEGFRGAAHPGD | |
| SCHEMBL7408187 | 0.69 | F10 (0.58) | F2F10F7GAA | |
| SCHEMBL7407441 | 0.68 | F10 (0.57) | F2F10F7 | |
| SCHEMBL7655135 | 0.68 | RAD52 (0.61) | GRIN1GRIN2BALDH1A1MAPTPKM | |
| SCHEMBL1638406 | 0.68 | ACSS2 (0.43) | MAPTHPGDACSS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |