Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 8/20 | 0.64 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692342 | 0.86 | ENPP2 (0.67) | LPLLIPGENPP2MGLLKDM4E | |
| SCHEMBL3132606 | 0.81 | ENPP2 (0.56) | LPLLIPGENPP2CA2MGLL | |
| SCHEMBL3138179 | 0.80 | LPL (0.90) | LPLLIPGENPP2CA1CA2 | |
| SCHEMBL8143762 | 0.78 | S1PR1 (0.41) | LPLLIPGENPP2 | |
| SCHEMBL1997891 | 0.78 | LIPG (1.00) | LPLLIPGENPP2CA1CA2 | |
| SCHEMBL28980699 | 0.77 | LIPG (1.00) | LPLLIPGENPP2CA1CA2 | |
| SCHEMBL28980689 | 0.77 | LIPG (1.00) | LPLLIPGENPP2CA1CA2 | |
| SCHEMBL28980712 | 0.77 | LIPG (1.00) | LPLLIPGENPP2CA1CA2 | |
| SCHEMBL28980647 | 0.77 | LIPG (1.00) | LPLLIPGENPP2CA1CA2 | |
| SCHEMBL3146386 | 0.77 | LIPG (1.00) | LPLLIPGENPP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | Pfizer Limited (GB) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029667-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LIMITED (GB) | 1999-06-17 | — | — | WO | disclosed |