Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.51 |
| ▸ | ITGAV | P06756 | 14/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403223 | 0.84 | ITGB3 (0.69) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL7407563 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2BITGAV | |
| SCHEMBL7407553 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2BITGAV | |
| SCHEMBL7396351 | 0.81 | ITGB3 (0.70) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL7405983 | 0.80 | ITGB3 (0.52) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| Trifluoroacetic Acid SCHEMBL7403171 | 0.79 | ITGB3 (0.65) | ITGB3ITGA2BITGAVITGB1ITGA5 | |
| SCHEMBL7982597 | 0.79 | ITGB3 (0.71) | ITGB3ITGA2BITGAV | |
| SCHEMBL7397410 | 0.78 | ITGB3 (0.53) | ITGB3ITGA2BITGAV | |
| SCHEMBL7404741 | 0.78 | ITGB3 (0.55) | ITGB3ITGA2BITGAV | |
| SCHEMBL8548583 | 0.76 | ITGB3 (0.52) | ITGB3ITGA2BITGAVITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037492-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |