Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.73 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.73 |
| ▸ | ITGAV | P06756 | 17/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407563 | 1.00 | ITGB3 (0.73) | ITGB3ITGA2BITGAV | |
| SCHEMBL7403221 | 0.84 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7404155 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL7396344 | 0.80 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7405981 | 0.79 | ITGB3 (0.74) | ITGB3ITGA2BITGAV | |
| SCHEMBL7406847 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BITGAV | |
| SCHEMBL7404739 | 0.77 | ITGB3 (0.79) | ITGB3ITGA2BITGAV | |
| SCHEMBL7397408 | 0.77 | ITGB3 (0.77) | ITGB3ITGA2BITGAV | |
| SCHEMBL7397150 | 0.77 | ALDH1A1 (0.43) | ITGB3ITGA2BITGAV | |
| SCHEMBL8548575 | 0.76 | ITGB3 (0.76) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037492-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |