Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399688 | 0.90 | ALDH1A1 (0.57) | RAB9AOPRM1NPC1TNFPAX8 | |
| SCHEMBL7400525 | 0.86 | MEN1 (0.55) | RAB9ANPC1LMNASMN1; SMN2HTT | |
| SCHEMBL7401572 | 0.84 | SMN1; SMN2 (0.60) | RAB9AOPRM1NPC1TNFPAX8 | |
| SCHEMBL9516076 | 0.83 | HRH3 (0.47) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL7393627 | 0.81 | HRH3 (0.47) | OPRM1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9513528 | 0.78 | CA1 (0.54) | LMNASMN1; SMN2CA1CA2CA7 | |
| SCHEMBL7396524 | 0.77 | MEN1 (0.53) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL7956461 | 0.75 | ALDH1A1 (0.54) | RAB9ALMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9513736 | 0.75 | POLB (0.49) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL7400645 | 0.75 | MEN1 (0.52) | LMNASMN1; SMN2HTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |