Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404875 | 0.90 | RAB9A (0.61) | ALDH1A1MEN1KMT2AOPRM1RAB9A | |
| SCHEMBL7400525 | 0.84 | MEN1 (0.55) | ALDH1A1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL9516076 | 0.82 | HRH3 (0.47) | ALDH1A1MEN1KMT2AHTTCA1 | |
| SCHEMBL7400469 | 0.81 | TBXA2R (0.45) | ALDH1A1MEN1KMT2ATBXA2RTBXAS1 | |
| SCHEMBL7401572 | 0.78 | SMN1; SMN2 (0.60) | ALDH1A1MEN1KMT2AOPRM1RAB9A | |
| SCHEMBL7396279 | 0.78 | POLB (0.60) | ALDH1A1MEN1KMT2AHTR1ALMNA | |
| SCHEMBL9513528 | 0.76 | CA1 (0.54) | LMNACA1CA2CA7CA9 | |
| SCHEMBL9080516 | 0.76 | MEN1 (0.50) | ALDH1A1MEN1KMT2AHTR1AHTT | |
| SCHEMBL6323362 | 0.75 | ITGB3 (0.48) | ALDH1A1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL7956788 | 0.75 | ITGB3 (0.48) | ALDH1A1MEN1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |