Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfotep. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfotep SCHEMBL2696245 | 0.98 | PPARD (0.46) | PPARDTSHRTDP1TP53MEN1 | |
| Sulfotep SCHEMBL628316 | 0.95 | PPARD (0.45) | PPARDTSHRTDP1TP53MEN1 | |
| Sulfotep SCHEMBL9561665 | 0.93 | PPARD (0.43) | PPARDTSHRTDP1TP53MEN1 | |
| Sulfotep SCHEMBL15687409 | 0.91 | PPARD (0.45) | PPARDTSHRTDP1TP53MEN1 | |
| Sulfotep SCHEMBL35637 | 0.87 | TDP1 (0.46) | PPARDTSHRTDP1TP53MEN1 | |
| Sulfotep SCHEMBL8191946 | 0.87 | TDP1 (0.46) | PPARDTSHRTDP1TP53MEN1 | |
| Sulfotep SCHEMBL461502 | 0.85 | TDP1 (0.39) | PPARDTSHRTDP1TP53MEN1 | |
| Sulfotep SCHEMBL10606468 | 0.84 | TDP1 (0.44) | PPARDTSHRTDP1TP53MEN1 | |
| Sulfotep SCHEMBL21060526 | 0.84 | TDP1 (0.44) | PPARDTSHRTDP1TP53MEN1 | |
| Sulfotep SCHEMBL22721240 | 0.84 | TSHR (0.45) | PPARDTSHRTDP1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 930 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024031075-A1 | MIXED COMPONENT TRACTION FLUIDS | VANTAGE SANTOLUBES RESEARCH LLC (US) | 2024-02-08 | — | — | WO | claimed |
| EP-3704217-B1 | ECOFRIENDLY AND BIODEGRADABLE LUBRICANT FORMULATION AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2023-11-29 | — | — | EP | claimed |
| CN-116041973-A | Anti-aging asphalt and preparation method and application thereof | 同济大学 | 2023-05-02 | — | — | CN | claimed |
| CN-115178381-A | Double-ligand type triazolethione collecting agent and preparation method and application thereof | 山东理工大学 | 2022-10-14 | — | — | CN | claimed |
| CN-113083514-B | Double-ligand type oxadiazole thioketone collecting agent and preparation method and application thereof | 山东理工大学 | 2022-05-27 | — | — | CN | claimed |
| US-11142718-B2 | Ecofriendly and biodegradable lubricant formulation and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-10-12 | — | — | US | claimed |
| CN-113083514-A | Double-ligand type oxadiazole thioketone collecting agent and preparation method and application thereof | 山东理工大学 | 2021-07-09 | — | — | CN | claimed |
| CN-112094292-A | Dithiophosphate end-capped mercaptosilane coupling agent and synthesis method and application thereof | 怡维怡橡胶研究院有限公司 | 2020-12-18 | — | — | CN | claimed |
| US-20200299602-A1 | ECOFRIENDLY AND BIODEGRADABLE LUBRICANT FORMULATION AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-09-24 | — | — | US | claimed |
| EP-3704217-A1 | ECOFRIENDLY AND BIODEGRADABLE LUBRICANT FORMULATION AND PROCESS FOR PREPARATION THEREOF | Council Of Scientific & Industrial Research (IN) | 2020-09-09 | — | — | EP | claimed |
| WO-2007066348-A1 | A COMPOSITION OF LUBRICATING OIL FOR TWO STROKE GASOLINE ENGINE AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-06-14 | — | — | WO | claimed |
| WO-2007066349-A1 | A COMPOSITION OF HYDRAULIC FLUID AND PROCESS FOR THE PREPARETION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-06-14 | — | — | WO | claimed |
| US-20070060486-A1 | Composition of hydraulic fluid and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-03-15 | — | — | US | claimed |
| WO-2001096504-A1 | FORMULATION WITH ESTER-CONTAINING BASESTOCKS HAVING REDUCED ENGINE WEAR | EXXON CHEMICAL PATENTS, INC. (US) | 2001-12-20 | — | — | WO | claimed |
| US-5242611-A | Electrical contact protective lubricant | GRIFFAW NORMAN E (US) | 1993-09-07 | — | — | US | claimed |
| EP-0540700-A1 | REACTION PRODUCTS OF A BORON COMPOUND AND A PHOSPHOLIPID, AND LUBRICANTS AND AQUEOUS FLUIDS CONTAINING SAME | THE LUBRIZOL CORPORATION (US) | 1993-05-12 | — | — | EP | claimed |
| WO-1992018586-A1 | REACTION PRODUCTS OF A BORON COMPOUND AND A PHOSPHOLIPID, AND LUBRICANTS AND AQUEOUS FLUIDS CONTAINING SAME | THE LUBRIZOL CORPORATION (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0372007-A1 | AMINOPLAST CATALYST AND COMPOSITIONS. | LUBRIZOL CORP (US) | 1990-06-13 | — | — | EP | claimed |
| WO-1989006250-A1 | AMINOPLAST CATALYST AND COMPOSITIONS | THE LUBRIZOL CORPORATION (US) | 1989-07-13 | — | — | WO | claimed |
| EP-0317348-A1 | Improved lubricant compositions for low-temperature internal combustion engines | EXXON CHEMICAL PATENTS INC. (US) | 1989-05-24 | — | — | EP | claimed |