Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfotep. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfotep SCHEMBL5016573 | 0.93 | MEN1 (0.38) | TDP1MEN1KMT2APPARDTSHR | |
| Sulfotep SCHEMBL11232718 | 0.93 | MEN1 (0.38) | TDP1MEN1KMT2APPARDTSHR | |
| Sulfotep SCHEMBL11233341 | 0.91 | MEN1 (0.36) | TDP1MEN1KMT2APPARDTSHR | |
| Sulfotep SCHEMBL7762968 | 0.91 | FFAR3 (0.46) | TDP1MEN1KMT2APPARDTSHR | |
| Sulfotep SCHEMBL1163901 | 0.91 | FFAR3 (0.46) | TDP1MEN1KMT2APPARDTSHR | |
| Sulfotep SCHEMBL53003 | 0.91 | ALOX15 (0.37) | TDP1MEN1KMT2APPARDTSHR | |
| Sulfotep SCHEMBL9717282 | 0.89 | ALOX15 (0.36) | TDP1MEN1KMT2APPARDTSHR | |
| Sulfotep SCHEMBL8336002 | 0.89 | ALOX15 (0.36) | TDP1MEN1KMT2APPARDTSHR | |
| Sulfotep SCHEMBL11870183 | 0.89 | ALOX15 (0.36) | TDP1MEN1KMT2APPARDTSHR | |
| Sulfotep SCHEMBL7657192 | 0.89 | ALOX15 (0.36) | TDP1MEN1KMT2APPARDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230326-A1 | FUNCTIONAL OR TELECHELIC POLYOLEFIN, DERIVATIVES THEREOF, AND PROCESS FOR PREPARING SAME | Université Claude Bernard Lyon 1 (FR) | 2017-10-18 | — | — | EP | claimed |
| WO-2016092227-A1 | FUNCTIONAL OR TELECHELIC POLYOLEFIN, DERIVATIVES THEREOF, AND PROCESS FOR PREPARING SAME | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2016-06-16 | — | — | WO | claimed |
| WO-2012033800-A1 | COMPOSITION AND METHOD FOR INHIBITING PREMATURE POLYMERIZATION | GENERAL ELECTRIC COMPANY (US) | 2012-03-15 | — | — | WO | claimed |
| US-5256710-A | Agitation, heat treatment | ASPHALT TECHNOLOGY & CONSULTANTS, INC. (US) | 1993-10-26 | — | — | US | claimed |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
| CN-113736038-A | Preparation method of photoresponse self-repairing fluorine-containing polyacrylate soap-free emulsion | 陕西科技大学 | 2021-12-03 | — | — | CN | disclosed |
| US-20210032181-A1 | DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-02-04 | — | — | US | disclosed |
| US-10329441-B2 | Aqueous pigment dispersion, pigment dispersant, and core-shell polymer particles | DIC CORPORATION (JP) | 2019-06-25 | — | — | US | disclosed |
| CN-107709372-A | Radiation curable ink composition | 图像电子公司 | 2018-02-16 | — | — | CN | disclosed |
| EP-3230292-A1 | TRANSFER AGENT FOR THE PREPARATION OF A FUNCTIONAL OR TELECHELIC POLYOLEFIN | Compagnie Générale des Etablissements Michelin (FR) | 2017-10-18 | — | — | EP | disclosed |
| EP-3230326-A1 | FUNCTIONAL OR TELECHELIC POLYOLEFIN, DERIVATIVES THEREOF, AND PROCESS FOR PREPARING SAME | Université Claude Bernard Lyon 1 (FR) | 2017-10-18 | — | — | EP | disclosed |
| EP-3081580-A1 | AQUEOUS PIGMENT DISPERSION, PIGMENT DISPERSANT, AND CORE-SHELL-TYPE POLYMER PARTICLES | DIC Corporation (JP) | 2016-10-19 | — | — | EP | disclosed |
| EP-0761477-B1 | PNEUMATIC TIRE | YOKOHAMA RUBBER CO LTD (JP) | 2002-08-07 | — | — | EP | disclosed |
| EP-1145872-A2 | Pneumatic tire | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5938869-A | Pneumatic tire with air permeation preventive layer | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0761477-A1 | PNEUMATIC TIRE | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0426930-A1 | Process for preserving wood | IBC Manufacturing Company (US) | 1991-05-15 | — | — | EP | disclosed |
| CN-1011765-B | PROCESS FOR FOAM FLOTATION OF S-CONTG. ORE | DOW CHEMICAL CO (US) | 1991-02-27 | — | — | CN | disclosed |
| US-4374142-A | RUBBER CURING AGENT, BIOCIDE FOR PLANTS | THIOKOL CORPORATION (US) | 1983-02-15 | — | — | US | disclosed |
| US-4182639-A | Method for improving the adhesion of brass-coated steel cord to rubber | UNITED STATES STEEL CORPORATION (US) | 1980-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032181-A1 | DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME | AFF2, AFF4, AFF1 | TDP1 2207/4885MEN1 398/4885KMT2A 349/4885 |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | AFF2, AFF4, AFF1 | TDP1 2207/4885MEN1 398/4885KMT2A 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.