Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742662 | 0.84 | DDB1 (0.44) | ALDH1A1DDB1CRBNCYP2C19SMN1; SMN2 | |
| SCHEMBL741732 | 0.81 | ALDH1A1 (0.51) | ALDH1A1DDB1CRBNKMT2AMAPK1 | |
| SCHEMBL744238 | 0.80 | ALDH1A1 (0.43) | ALDH1A1DDB1CRBNKMT2AMAPK1 | |
| SCHEMBL32674110 | 0.78 | ALDH1A1 (0.50) | ALDH1A1DDB1CRBNKMT2AMAPK1 | |
| SCHEMBL32674103 | 0.78 | ALDH1A1 (0.53) | ALDH1A1DDB1CRBNKMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL32674229 | 0.77 | ALDH1A1 (0.49) | ALDH1A1DDB1CRBNKMT2AMAPK1 | |
| SCHEMBL30968716 | 0.77 | ALDH1A1 (0.52) | ALDH1A1DDB1CRBNKMT2AMAPK1 | |
| SCHEMBL30968715 | 0.77 | ALDH1A1 (0.52) | ALDH1A1DDB1CRBNKMT2AMAPK1 | |
| SCHEMBL2542693 | 0.77 | DDB1 (0.54) | ALDH1A1DDB1CRBNKMT2AMAPK1 | |
| SCHEMBL903571 | 0.76 | MAOA (0.50) | ALDH1A1DDB1CRBNKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |