Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24425844 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1LMNADDB1 | |
| SCHEMBL740570 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1LMNADDB1 | |
| SCHEMBL2542693 | 0.79 | DDB1 (0.54) | ALDH1A1MAPK1L3MBTL1LMNADDB1 | |
| Hydrochloric Acid SCHEMBL2805409 | 0.78 | DDB1 (0.52) | ALDH1A1MAPK1L3MBTL1LMNADDB1 | |
| SCHEMBL1144346 | 0.77 | DDB1 (0.51) | ALDH1A1MAPK1L3MBTL1LMNADDB1 | |
| SCHEMBL23460656 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1LMNADDB1 | |
| SCHEMBL3192 | 0.77 | DDB1 (0.51) | ALDH1A1MAPK1L3MBTL1LMNADDB1 | |
| SCHEMBL24425843 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL741795 | 0.76 | DDB1 (0.51) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL743375 | 0.76 | DDB1 (0.42) | ALDH1A1MAPK1L3MBTL1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-7935824-B2 | Ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |