Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402091 | 0.97 | ELANE (0.46) | ELANEANPEPRNPEPDNPEPMMP3 | |
| SCHEMBL8508599 | 0.91 | MMP3 (0.42) | ELANEANPEPRNPEPDNPEPMMP3 | |
| SCHEMBL8511173 | 0.89 | MMP3 (0.42) | ELANEMMP3MMP1ACHEMAOB | |
| SCHEMBL7404562 | 0.86 | ACHE (0.41) | ACHEMAOBTDP1L3MBTL1CASP3 | |
| SCHEMBL7384535 | 0.80 | ELANE (0.44) | ELANEANPEPRNPEPDNPEPMMP3 | |
| SCHEMBL8510656 | 0.78 | MMP3 (0.38) | MMP3MMP1ACHEMAOBMMP9 | |
| SCHEMBL29009464 | 0.77 | ANPEP (0.46) | ANPEPRNPEPDNPEPMMP9MMP2 | |
| SCHEMBL7593717 | 0.76 | ELANE (0.44) | ELANEMMP3MMP1ACHEMAOB | |
| SCHEMBL8763029 | 0.76 | ELANE (0.40) | ELANEANPEPRNPEPDNPEPMMP3 | |
| SCHEMBL7407118 | 0.75 | LARS1 (0.41) | ANPEPRNPEPDNPEPMMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824543-A1 | PEPTIDE COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION, AND THEIR THERAPEUTIC USE | Chiroscience Limited (GB) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035711-A1 | PEPTIDE COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION, AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-14 | — | — | WO | disclosed |