Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 0.42 |
| ▸ | MMP1 | P03956 | 8/20 | 0.42 |
| ▸ | MMP2 | P08253 | 7/20 | 0.42 |
| ▸ | MMP9 | P14780 | 6/20 | 0.42 |
| ▸ | MMP7 | P09237 | 3/20 | 0.42 |
| ▸ | MMP14 | P50281 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511173 | 0.97 | MMP3 (0.42) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7405706 | 0.91 | ELANE (0.47) | MMP3MMP1MMP2MMP9ELANE | |
| SCHEMBL7402091 | 0.89 | ELANE (0.46) | MMP3MMP1MMP2ELANEMAOB | |
| SCHEMBL8510656 | 0.87 | MMP3 (0.38) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7407118 | 0.85 | LARS1 (0.41) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7593717 | 0.84 | ELANE (0.44) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7403302 | 0.82 | MMP1 (0.48) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7403458 | 0.82 | LARS1 (0.44) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7595170 | 0.82 | ELANE (0.46) | MMP3MMP1MMP2MMP9MMP7 | |
| SCHEMBL7402161 | 0.82 | MMP3 (0.48) | MMP3MMP1MMP2MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981491-A | PEPTIDES; METALLOENZYMES; TUMOR NECROSIS FACTOR | DARWIN DISCOVERY LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |