Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | CBFB | Q13951 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8159907 | 0.99 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL7821732 | 0.91 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| Hydrochloric Acid SCHEMBL8159913 | 0.90 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL7831103 | 0.89 | SMN1; SMN2 (0.55) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL7834555 | 0.89 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL7830510 | 0.89 | MAOA (0.45) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| Hydrochloric Acid SCHEMBL8142732 | 0.88 | SMN1; SMN2 (0.54) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| Hydrochloric Acid SCHEMBL8148413 | 0.88 | MAOA (0.44) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| Hydrochloric Acid SCHEMBL8149742 | 0.88 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL7833679 | 0.87 | ADH5 (0.48) | RAB9ANPC1SMN1; SMN2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | claimed |
| US-6040327-A | INHIBITORS OF INTERLEUKINS; TREATING RHEUMATOID ARTHRITIS OR ARTHROSIS | ADIR ET COMPAGNIE (FR) | 2000-03-21 | — | — | US | claimed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | claimed |
| JP-11100368-A | — | — | None | — | — | JP | disclosed |
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| US-6040327-A | INHIBITORS OF INTERLEUKINS; TREATING RHEUMATOID ARTHRITIS OR ARTHROSIS | ADIR ET COMPAGNIE (FR) | 2000-03-21 | — | — | US | disclosed |
| JP-H11100368-A | NEW BENZIMIDAZOLE, BENZOXAZOLE AND BENZOTHIAZOLE COMPOUND AND PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ADIR | 1999-04-13 | — | — | JP | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |