Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.45 |
| ▸ | TCF4 | P15884 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514090 | 0.93 | MEN1 (0.52) | CYP2C9ALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL7407140 | 0.88 | PLAU (0.50) | ALDH1A1GAAMEN1KMT2ATDP1 | |
| SCHEMBL7407271 | 0.88 | F10 (0.51) | ALDH1A1NPSR1GAAMEN1KMT2A | |
| SCHEMBL7407210 | 0.85 | CYP2C9 (0.62) | CYP2C9ALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL7411341 | 0.80 | MEN1 (0.65) | CYP2C9ALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL7411939 | 0.80 | MEN1 (0.60) | NPSR1GAAMEN1KMT2AHDAC3 | |
| SCHEMBL7402259 | 0.79 | MEN1 (0.67) | CYP2C9ALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL8417467 | 0.78 | KMT2A (0.53) | ALDH1A1MEN1KMT2AF10MAPK1 | |
| SCHEMBL8415881 | 0.78 | ALDH1A1 (0.47) | CYP2C9ALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL7407190 | 0.78 | F10 (0.68) | CYP2C9ALDH1A1NPSR1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | claimed |
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |