Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411939 | 0.91 | MEN1 (0.60) | F10KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL8417467 | 0.89 | KMT2A (0.53) | F10KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7407367 | 0.88 | CYP2C9 (0.52) | F10KMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL7410953 | 0.87 | ALDH1A1 (0.47) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL7407190 | 0.85 | F10 (0.68) | F10KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7404902 | 0.85 | F10 (0.68) | F10KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7413373 | 0.84 | CREBBP (0.44) | F10KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7411059 | 0.81 | F10 (0.57) | F10KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL7410267 | 0.81 | F10 (0.57) | F10KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL8414166 | 0.81 | CHEK1 (0.51) | F10KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | claimed |
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | disclosed |
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |