Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | F10 | P00742 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402259 | 0.97 | MEN1 (0.67) | MEN1KMT2AHDAC3NCOR2HDAC1 | |
| SCHEMBL7407210 | 0.88 | CYP2C9 (0.62) | MEN1KMT2AHDAC3NCOR2HDAC1 | |
| SCHEMBL7410644 | 0.88 | MEN1 (0.84) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL7409183 | 0.88 | MEN1 (0.84) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL7514090 | 0.86 | MEN1 (0.52) | MEN1KMT2AHDAC3NCOR2HDAC1 | |
| SCHEMBL7413497 | 0.83 | SLC16A3 (0.52) | KMT2AF10ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7411588 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AHDAC3NCOR2HDAC1 | |
| SCHEMBL7407367 | 0.80 | CYP2C9 (0.52) | MEN1KMT2AHDAC3NCOR2HDAC1 | |
| SCHEMBL7411350 | 0.80 | GPR27 (0.51) | MEN1KMT2AF10ALDH1A1LMNA | |
| SCHEMBL8415881 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2AHDAC3NCOR2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | claimed |
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | disclosed |
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |