Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 4/20 | 0.46 |
| ▸ | HTR1B | P28222 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403681 | 0.89 | HTR1F (0.56) | HTR1FHTR1DHTR1BSLC6A4L3MBTL1 | |
| SCHEMBL7408494 | 0.85 | HTR1F (0.58) | HTR1FHTR1DHTR1BSLC6A4NR2E1 | |
| SCHEMBL7407846 | 0.85 | DRD2 (0.50) | HTR1FHTR1DHTR1BNR2E1RXFP1 | |
| Hydrochloric Acid SCHEMBL7409354 | 0.84 | HTR1F (0.49) | HTR1FHTR1DHTR1BNR2E1RXFP1 | |
| SCHEMBL7404381 | 0.83 | HTR1F (0.50) | HTR1FHTR1DHTR1BSLC6A4NR2E1 | |
| SCHEMBL7407989 | 0.83 | HTR1D (0.55) | HTR1FHTR1DHTR1BSLC6A4HTR6 | |
| Hydrochloric Acid SCHEMBL7405179 | 0.82 | HTR1D (0.54) | HTR1FHTR1DHTR1BSLC6A4HTR6 | |
| Cyclindole SCHEMBL122715 | 0.81 | NR2E1 (0.61) | HTR1FHTR1DHTR1BNR2E1HTR6 | |
| SCHEMBL7415699 | 0.81 | KMT2A (0.58) | HTR1FHTR1DHTR1BL3MBTL1 | |
| Cyclindole SCHEMBL7412314 | 0.80 | NR2E1 (0.60) | HTR1FHTR1DHTR1BSLC6A4NR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |