Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 7/20 | 0.42 |
| ▸ | HTR1D | P28221 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413233 | 0.89 | HTR1F (0.52) | HTR1FHTR1BHTR1DKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7408517 | 0.88 | HTR1F (0.51) | HTR1FHTR1BHTR1DKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7410143 | 0.88 | HTR1F (0.48) | HTR1FHTR1BHTR1DKMT2AMEN1 | |
| SCHEMBL11418721 | 0.84 | HTR1F (0.52) | HTR1FHTR1BHTR1DKMT2AMEN1 | |
| SCHEMBL7407453 | 0.83 | HTR1F (0.48) | HTR1FHTR1BHTR1DCHRM3NR2E1 | |
| SCHEMBL7403681 | 0.83 | HTR1F (0.56) | HTR1FHTR1BHTR1DKMT2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL11432883 | 0.83 | HTR1F (0.51) | HTR1FHTR1BHTR1DKMT2AMEN1 | |
| SCHEMBL7412967 | 0.82 | CHRM2 (0.48) | HTR1FHTR1BHTR1DKMT2AMEN1 | |
| SCHEMBL11419087 | 0.80 | HTR1F (0.53) | HTR1FHTR1BHTR1DKMT2AMEN1 | |
| SCHEMBL7407128 | 0.79 | HTR1F (0.67) | HTR1FHTR1BHTR1DKMT2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087946-A1 | ARYL ALKANOYLPYRIDAZINES | MERCK PATENT GmbH (DE) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065880-A1 | ARYL ALKANOYLPYRIDAZINES | MERCK PATENT GMBH (DE) | 1999-12-23 | — | — | WO | disclosed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |