Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.56 |
| ▸ | CTSL | P07711 | 6/20 | 0.55 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | TACR2 | P21452 | 4/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408205 | 1.00 | CTSS (0.56) | CTSSCTSLCTSBTACR2CTSK | |
| SCHEMBL7356291 | 0.78 | FKBP1A (0.41) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7404835 | 0.77 | CTSS (0.61) | CTSSCTSLCTSBTACR2POLB | |
| SCHEMBL7408631 | 0.77 | CTSS (0.61) | CTSSCTSLCTSBTACR2POLB | |
| SCHEMBL7354024 | 0.77 | CTSL (0.83) | CTSSCTSLCTSBTACR2CTSK | |
| SCHEMBL7354034 | 0.77 | CTSL (0.83) | CTSSCTSLCTSBTACR2CTSK | |
| SCHEMBL7354020 | 0.77 | CTSL (0.83) | CTSSCTSLCTSBTACR2CTSK | |
| SCHEMBL10778417 | 0.76 | CTSS (0.62) | CTSSCTSLCTSBTACR2POLB | |
| SCHEMBL5193787 | 0.75 | POLB (0.74) | CTSSCTSLCTSBTACR2POLB | |
| SCHEMBL7275964 | 0.75 | POLB (0.74) | CTSSCTSLCTSBTACR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0817778-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030353-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-10-03 | — | — | WO | disclosed |