SCHEMBL7408304

SCHEMBL7408304

CNC(=O)[C@H](Cc1ccccc1)N(C(=O)CC(=O)OC)C(=O)[C@@H](N)CC(C)C

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 9/20 0.45
ANPEP P15144 2/20 0.42
RNPEP Q9H4A4 1/20 0.42
DNPEP Q9ULA0 1/20 0.42
MMP2 P08253 5/20 0.40
MMP3 P08254 4/20 0.40
LTA4H P09960 1/20 0.40
MMP9 P14780 3/20 0.39
MMP8 P22894 3/20 0.39
MMP7 P09237 2/20 0.39
FCER2 P06734 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7400676 0.88 ANPEP (0.44) MMP1ANPEPRNPEPDNPEPMMP2
SCHEMBL7404474 0.86 ANPEP (0.43) MMP1ANPEPRNPEPDNPEPMMP2
SCHEMBL8510054 0.86 ANPEP (0.43) MMP1ANPEPRNPEPDNPEPMMP2
SCHEMBL8764880 0.85 ANPEP (0.42) MMP1ANPEPRNPEPDNPEPMMP2
SCHEMBL7403732 0.85 LTA4H (0.42) MMP1ANPEPRNPEPDNPEPMMP2
SCHEMBL8764855 0.85 MMP1 (0.48) MMP1ANPEPRNPEPDNPEPMMP2
SCHEMBL6414163 0.84 ANPEP (0.47) MMP1ANPEPRNPEPDNPEPMMP2
SCHEMBL8015476 0.83 ACE (0.43) MMP1ANPEPRNPEPDNPEPMMP2
SCHEMBL6414041 0.83 MME (0.48) MMP1ANPEPRNPEPDNPEPMMP2
SCHEMBL6412473 0.82 ANPEP (0.46) MMP1ANPEPRNPEPDNPEPMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996032382-A1 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS SANOFI (FR) 1996-10-17 WO claimed
WO-1996032382-A1 1-PHENYLPYRAZOLE-3-CARBOXAMIDES ACTING ON NEUROTENSIN RECEPTORS SANOFI (FR) 1996-10-17 WO disclosed