Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 7/20 | 0.41 |
| ▸ | MMP2 | P08253 | 6/20 | 0.41 |
| ▸ | MMP3 | P08254 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP7 | P09237 | 2/20 | 0.40 |
| ▸ | FCER2 | P06734 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400676 | 0.91 | ANPEP (0.44) | ANPEPRNPEPDNPEPPSMB5LTA4H | |
| SCHEMBL8764880 | 0.90 | ANPEP (0.42) | ANPEPRNPEPDNPEPLTA4HMMP1 | |
| SCHEMBL7403732 | 0.90 | LTA4H (0.42) | ANPEPRNPEPDNPEPLTA4HMMP1 | |
| SCHEMBL8015476 | 0.86 | ACE (0.43) | ANPEPRNPEPDNPEPMMP1MMP2 | |
| SCHEMBL7408304 | 0.86 | MMP1 (0.45) | ANPEPRNPEPDNPEPLTA4HMMP1 | |
| SCHEMBL6418589 | 0.85 | ANPEP (0.44) | ANPEPRNPEPDNPEPMMP1MMP2 | |
| SCHEMBL6414163 | 0.84 | ANPEP (0.47) | ANPEPRNPEPDNPEPMMP1MMP2 | |
| SCHEMBL7397719 | 0.84 | ELANE (0.44) | ANPEPRNPEPDNPEPMMP1MMP2 | |
| SCHEMBL6414041 | 0.83 | MME (0.48) | ANPEPRNPEPDNPEPMMP1MMP2 | |
| SCHEMBL7403302 | 0.83 | MMP1 (0.48) | MMP1MMP2MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981491-A | PEPTIDES; METALLOENZYMES; TUMOR NECROSIS FACTOR | DARWIN DISCOVERY LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |