Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | USP14 | P54578 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414266 | 0.85 | PTGS1 (0.46) | HTR6 | |
| SCHEMBL7407904 | 0.83 | HTR6 (0.51) | HTR6MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7406680 | 0.80 | HTR6 (0.46) | HTR6MEN1ALDH1A1KMT2ACYP2D6 | |
| SCHEMBL7414173 | 0.77 | HTR6 (0.50) | HTR6CYP2D6 | |
| SCHEMBL7408736 | 0.76 | HTR6 (0.52) | HTR6CYP2D6 | |
| SCHEMBL7403630 | 0.70 | CYP19A1 (0.50) | HTR6ALDH1A1HPGDKDM4ECYP2D6 | |
| SCHEMBL7410787 | 0.69 | HTR2A (0.47) | HTR6LMNAMAPT | |
| SCHEMBL7415797 | 0.65 | CYP2D6 (0.40) | HTR6MEN1KMT2ACYP2D6CYP1A2 | |
| SCHEMBL7463173 | 0.65 | CGAS (0.38) | HTR6CYP2D6CYP1A2LMNAMAPT | |
| SCHEMBL14533266 | 0.65 | CA1 (0.50) | HTR6MEN1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |