Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 5/20 | 0.39 |
| ▸ | CDK2 | P24941 | 5/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CCNT2 | O60583 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742471 | 0.84 | CCNE1 (0.45) | CCNE1CDK2ADORA3ADORA2ACCNT1 | |
| SCHEMBL743586 | 0.80 | ADORA3 (0.60) | ADORA3ADORA2AADORA1 | |
| SCHEMBL743587 | 0.80 | ADORA3 (0.60) | ADORA3ADORA2AADORA1 | |
| SCHEMBL8149501 | 0.70 | ADORA3 (0.63) | ADORA3ADORA2AADORA1 | |
| SCHEMBL773397 | 0.70 | ADORA3 (0.46) | ADORA3ADORA2AADORA1 | |
| SCHEMBL743870 | 0.70 | ADORA3 (0.57) | ADORA3ADORA2AADORA1 | |
| SCHEMBL743869 | 0.70 | ADORA3 (0.57) | ADORA3ADORA2AADORA1 | |
| SCHEMBL742472 | 0.69 | SMN1; SMN2 (0.48) | CDK2 | |
| SCHEMBL740871 | 0.68 | ADORA3 (0.64) | ADORA3ADORA2AADORA1 | |
| SCHEMBL774632 | 0.68 | ADORA3 (0.64) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430036-A1 | SUBSTITUTED 6-(BENZYLAMINO) PURINE RIBOSIDE DERIVATIVES, USE THEREOF AND COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130233-A1 | SUBSTITUTED 6-(BENZYLAMINO) PURINE RIBOSIDE DERIVATIVES, USE THEREOF AND COMPOSITIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2010-11-18 | — | — | WO | disclosed |