SCHEMBL7409018

SCHEMBL7409018

CCC(O)c1ccccc1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
KCNQ2 O43526 1/20 0.41
MAPT P10636 1/20 0.41
RECQL P46063 1/20 0.41
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
BCL2L1 Q07817 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
TSHR P16473 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
BACE1 P56817 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27576572 0.88 LMNA (0.44) LMNAMAPTRECQLPDCD1CD274
SCHEMBL5907398 0.87 LMNA (0.54) LMNAMAPTRECQLALDH1A1HPGD
SCHEMBL8125623 0.85 LMNA (0.41) LMNAMAPTALDH1A1HPGDTSHR
SCHEMBL5907405 0.85 LMNA (0.46) LMNAKCNQ2MAPTRECQLALDH1A1
SCHEMBL27484572 0.85 LMNA (0.42) LMNAKCNQ2MAPTRECQLALDH1A1
SCHEMBL11334274 0.85 CHRM1 (0.40) LMNAKCNQ2MAPTALDH1A1HPGD
SCHEMBL7012979 0.83 ALDH1A1 (0.43) LMNAALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL31376578 0.83 ALDH1A1 (0.43) LMNAALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL7012982 0.83 ALDH1A1 (0.43) LMNAALDH1A1HPGDBCL2L1HSD17B10
SCHEMBL22445659 0.82 DPP4 (0.47) ALDH1A1HPGDBCL2L1HSD17B10PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111918891-B Curable composition and cured product thereof DIC株式会社 2023-02-28 CN disclosed
CN-112105661-B Acid group-containing (meth) acrylate resin composition, curable resin composition, cured product, and resin material for solder resist DIC株式会社 2023-02-24 CN disclosed
CN-110770202-B Active ester resin, and composition and cured product using same DIC株式会社 2022-12-16 CN disclosed
CN-112119104-A Epoxy (meth) acrylate resin composition, curable resin composition, cured product, and article DIC株式会社 2020-12-22 CN disclosed
CN-112105661-A Acid group-containing (meth) acrylate resin composition, curable resin composition, cured product, insulating material, resin material for solder resist, and protective member DIC株式会社 2020-12-18 CN disclosed
CN-111918891-A Curable composition and cured product thereof DIC株式会社 2020-11-10 CN disclosed
CN-110770202-A Active ester resin, and composition and cured product using same DIC株式会社 2020-02-07 CN disclosed
CN-102300899-B Epoxy resin composition, process for producing the epoxy resin composition, and cured object formed therefrom MEIWA PLASTIC IND LTD 2013-08-07 CN disclosed
CN-102300899-A Epoxy resin composition, process for producing the epoxy resin composition, and cured object formed therefrom 2011-12-28 CN disclosed
CN-101233165-B Low softening point novolak resin, method for producing the same, and cured epoxy resin using the same UBE INDUSTRIES 2011-08-31 CN disclosed
CN-101233165-A Low softening point novolak resin, method for producing the same, and cured epoxy resin using the same UBE INDUSTRIES (JP) 2008-07-30 CN disclosed
EP-0682663-B1 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS UPJOHN CO (US) 2001-04-18 EP disclosed
US-6133446-A Heterocyclic compounds for the treatment of CNS and cardiovascular disorders PHARMACIA & UPJOHN COMPANY (US) 2000-10-17 US disclosed
EP-0737189-B1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS UPJOHN CO (US) 1999-07-28 EP disclosed
US-5877317-A Heterocyclic compounds for the treatment of CNS and cardiovascular disorders PHARMACIA & UPJOHN COMPANY (US) 1999-03-02 US disclosed
WO-1995018118-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS THE UPJOHN COMPANY (US) 1995-07-06 WO disclosed