SCHEMBL7012979

SCHEMBL7012979

OC[C@H](O)c1ccccc1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
HPGD P15428 1/20 0.43
BCL2L1 Q07817 1/20 0.43
KMT2A Q03164 1/20 0.41
BACE1 P56817 1/20 0.39
DPP4 P27487 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
CYP2A6 P11509 1/20 0.38
MAPK1 P28482 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
PYGL P06737 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7012982 1.00 ALDH1A1 (0.43) ALDH1A1HSD17B10HPGDBCL2L1KMT2A
SCHEMBL31376578 1.00 ALDH1A1 (0.43) ALDH1A1HSD17B10HPGDBCL2L1KMT2A
SCHEMBL1338708 0.86 LMNA (0.36) CHRM1CHRM3LMNAPPARAPPARG
SCHEMBL22445659 0.85 DPP4 (0.47) ALDH1A1HSD17B10HPGDBCL2L1KMT2A
SCHEMBL31376568 0.84 CYP1A2 (0.40) ALDH1A1HSD17B10CHRM1CHRM3PYGL
SCHEMBL2323698 0.84 PDCD1 (0.38) ALDH1A1HSD17B10HPGDBCL2L1KMT2A
SCHEMBL6474648 0.83 ALDH1A1 (0.40) ALDH1A1HSD17B10HPGDBCL2L1KMT2A
SCHEMBL7409018 0.83 LMNA (0.52) ALDH1A1HSD17B10HPGDBCL2L1KMT2A
SCHEMBL1549219 0.81 LMNA (0.39) LMNAADRB2
SCHEMBL11334274 0.80 CHRM1 (0.40) ALDH1A1HSD17B10HPGDBCL2L1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1346767-A1 Multifunctional catalyst useful in the synthesis of chiral vicinal diols and process for the preparation thereof Council of Scientific and Industrial Research (IN) 2003-09-24 EP disclosed