Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410203 | 0.77 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL7407231 | 0.76 | PTGDR2 (0.56) | PTGDR2 | |
| SCHEMBL7403808 | 0.73 | HTR6 (0.45) | HTR6 | |
| SCHEMBL7406680 | 0.73 | HTR6 (0.46) | PTGDR2TBXA2RPTGDRHTR6CYP2D6 | |
| SCHEMBL7407214 | 0.72 | MAPT (0.40) | HTR6CYP2D6 | |
| SCHEMBL7411899 | 0.71 | TSHR (0.46) | PTGDR2AKR1B10AKR1B1 | |
| SCHEMBL7414173 | 0.70 | HTR6 (0.50) | PTGDR2TBXA2RPTGDRHTR6CYP2D6 | |
| SCHEMBL7407904 | 0.70 | HTR6 (0.51) | HTR6CYP2D6 | |
| SCHEMBL7405351 | 0.70 | PTGDR2 (0.43) | PTGDR2CYP2D6 | |
| SCHEMBL7414266 | 0.69 | PTGS1 (0.46) | PTGDR2TBXA2RPTGDRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |