SCHEMBL7409143

SCHEMBL7409143

Cc1c(F)ccc2[nH]c3c(c12)CC(N(C)C)CC3

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR1F P30939 1/20 0.47
HTR1D P28221 5/20 0.41
HTR1B P28222 4/20 0.41
HTR1A P08908 5/20 0.38
HTR7 P34969 5/20 0.38
CHRM3 P20309 2/20 0.36
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
HTR6 P50406 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7410356 0.99 HTR1F (0.46) HTR1FHTR1DHTR1BHTR1AHTR7
SCHEMBL7408361 0.83 HTR1A (0.50) HTR1FHTR1DHTR1BHTR1AHTR7
SCHEMBL7408119 0.80 HTR1F (0.42) HTR1FHTR1DHTR1BHTR1AHTR7
SCHEMBL7413369 0.79 HTR1F (0.42) HTR1FHTR1DHTR1BHTR1AHTR7
SCHEMBL7410925 0.78 CHRM3 (0.43) HTR1FHTR1DHTR1BHTR1AHTR7
SCHEMBL7408846 0.75 HTR1F (0.41) HTR1FHTR1DHTR1BHTR1AHTR7
SCHEMBL7410902 0.75 HTR1F (0.39) HTR1FHTR1DHTR1BHTR1AHTR7
SCHEMBL7405543 0.75 HTR1A (0.47) HTR1FHTR1DHTR1BHTR1AHTR7
SCHEMBL7407128 0.75 HTR1F (0.67) HTR1FHTR1DHTR1BHTR1AHTR6
SCHEMBL7402841 0.74 HTR1F (0.42) HTR1FHTR1DHTR1BHTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4257952-A PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES STERLING DRUG INC. (US) 1981-03-24 US disclosed
US-4180673-A USED FOR TRANSFER TAPES IN PRODUCTION OF PRINTED CIRCUITS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-12-25 US disclosed
US-4172834-A ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS STERLING DRUG INC. (US) 1979-10-30 US disclosed
US-4062864-A ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1977-12-13 US disclosed
US-3959309-A ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1976-05-25 US disclosed