Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6220784 | 1.00 | F10 (0.46) | F10DGAT1MAP4K4METHSP90AB1 | |
| Trifluoroacetic Acid SCHEMBL7921756 | 0.96 | F10 (0.43) | F10DGAT1MAP4K4METHSP90AB1 | |
| SCHEMBL6221508 | 0.93 | F10 (0.49) | F10DGAT1MAP4K4 | |
| Trifluoroacetic Acid SCHEMBL7213639 | 0.93 | DGAT1 (0.39) | F10DGAT1MAP4K4 | |
| Trifluoroacetic Acid SCHEMBL7545753 | 0.89 | F10 (0.45) | F10DGAT1HSP90AB1 | |
| Trifluoroacetic Acid SCHEMBL6220788 | 0.89 | F10 (0.45) | F10DGAT1HSP90AB1 | |
| Trifluoroacetic Acid SCHEMBL7409149 | 0.89 | F10 (0.45) | F10DGAT1HSP90AB1 | |
| Trifluoroacetic Acid SCHEMBL7923391 | 0.87 | MET (0.40) | F10MET | |
| Trifluoroacetic Acid SCHEMBL7915310 | 0.87 | MET (0.40) | F10MET | |
| Trifluoroacetic Acid SCHEMBL7214503 | 0.85 | F10 (0.47) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086099-A4 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2002-01-02 | — | — | EP | claimed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | claimed |
| EP-1086099-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | Aventis Pharmaceuticals Products Inc. (US) | 2001-03-28 | — | — | EP | claimed |
| WO-1999062904-A1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-12-09 | — | — | WO | claimed |
| US-6281227-B1 | INHIBITORS OF THE ACTIVITY OF FACTOR XA. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-08-28 | — | — | US | disclosed |