Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860932 | 0.82 | CES2 (0.46) | L3MBTL1ATMGAANPC1CES2 | |
| SCHEMBL11324996 | 0.80 | SLC6A3 (0.40) | TDP1NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL23091851 | 0.78 | TDP1 (0.50) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL408412 | 0.78 | TDP1 (0.50) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL27713890 | 0.78 | CES2 (0.53) | L3MBTL1NPC1RAB9ACES2CES1 | |
| Water SCHEMBL27597000 | 0.78 | TDP1 (0.54) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL11296743 | 0.77 | LMNA (0.44) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL7342834 | 0.77 | LMNA (0.52) | TDP1L3MBTL1ATMGAAHSP90AA1 | |
| SCHEMBL395491 | 0.77 | MDM2 (0.48) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL10741256 | 0.75 | TDP1 (0.47) | TDP1L3MBTL1ATMGAAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115184478-A | Quantitative analysis method of 70 amino substances in blood plasma based on 'derivatization in fiber' strategy and application thereof | 沈阳药科大学 | 2022-10-14 | — | — | CN | claimed |
| CN-107782834-B | Rapid analysis method for biogenic amine in fish | 中国科学院大连化学物理研究所 | 2020-02-21 | — | — | CN | claimed |
| CN-107383057-B | Imidazoles [4,5-e] thiophene [2,3-b] pyridine derivatives and preparation method thereof with the double fluorescent functionals of solid-liquid | 中山大学 | 2019-04-30 | — | — | CN | claimed |
| CN-107383057-A | Imidazoles [4,5 e] thiophene [2,3 b] pyridine derivatives with the double fluorescent functionals of solid-liquid and preparation method thereof | 中山大学 | 2017-11-24 | — | — | CN | claimed |
| CN-115184478-A | Quantitative analysis method of 70 amino substances in blood plasma based on 'derivatization in fiber' strategy and application thereof | 沈阳药科大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-113447575-A | Method for determining dalbavancin impurities | 重庆乾泰生物医药有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-112730699-A | Method and kit for detecting catecholamine and metabolites in blood plasma | 杭州汉库医学检验所有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-107782834-B | Rapid analysis method for biogenic amine in fish | 中国科学院大连化学物理研究所 | 2020-02-21 | — | — | CN | disclosed |
| CN-110606850-A | 3-benzo [4,5] imidazo [1,2-a ] pyrazine-1-amine compound and preparation method and application thereof | 中山大学 | 2019-12-24 | — | — | CN | disclosed |
| CN-107383057-B | Imidazoles [4,5-e] thiophene [2,3-b] pyridine derivatives and preparation method thereof with the double fluorescent functionals of solid-liquid | 中山大学 | 2019-04-30 | — | — | CN | disclosed |
| CN-108774201-A | A kind of synthetic method of 4H- pyran compounds | 安徽古尔特科技有限公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-107586469-A | Color compositions, coloured composition and cured composition for color | 住友化学株式会社 | 2018-01-16 | — | — | CN | disclosed |
| EP-0315698-A1 | THIENO(TRIAZOLO)DIAZEPINE COMPOUNDS AND MEDICINAL APPLICATION OF THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-05-17 | — | — | EP | disclosed |
| EP-0194416-B1 | THIENO-TRIAZOLO-1,4-DIAZEPINO-2-CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM KG (DE) | 1989-04-26 | — | — | EP | disclosed |
| US-4820703-A | TREATMENT OF INFLAMMATORY, RESPIRATORY AND CARDIOVASCULAR DISEASES | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1989-04-11 | — | — | US | disclosed |
| EP-0268242-A1 | PAF-antagonistic thienotriazolodiazepine compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-05-25 | — | — | EP | disclosed |
| EP-0254245-A1 | Hetrazepins and processes for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1988-01-27 | — | — | EP | disclosed |
| EP-0240899-A2 | 1,4-Diazepine | BOEHRINGER INGELHEIM KG (DE) | 1987-10-14 | — | — | EP | disclosed |
| EP-0230942-A2 | Thieno-1,4-diazepines | BOEHRINGER INGELHEIM KG (DE) | 1987-08-05 | — | — | EP | disclosed |
| EP-0194416-A1 | Thieno-triazolo-1,4-diazepino-2-carboxamides, process for their preparation and pharmaceutical compositions | BOEHRINGER INGELHEIM KG (DE) | 1986-09-17 | — | — | EP | disclosed |