Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DTYMK | P23919 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415129 | 0.94 | CHRNB2 (0.40) | SSTR4GPR119CHRNB2CHRNA4GCK | |
| SCHEMBL7413163 | 0.73 | NPC1 (0.35) | CHRNB2CHRNA4 | |
| SCHEMBL7413347 | 0.72 | CHRNB2 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL14632750 | 0.71 | LMNA (0.37) | POLB | |
| SCHEMBL2300520 | 0.69 | DGAT1 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL2185911 | 0.69 | DGAT1 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL28503989 | 0.68 | POLB (0.50) | GPR119GCKPOLBDTYMK | |
| SCHEMBL6294817 | 0.67 | CHRNB2 (0.39) | SSTR4GPR119CHRNB2CHRNA4 | |
| SCHEMBL7409193 | 0.67 | CHRNB2 (0.54) | SSTR4GPR119CHRNB2CHRNA4GCK | |
| SCHEMBL7453857 | 0.67 | CHRNB2 (0.54) | SSTR4GPR119CHRNB2CHRNA4GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047690-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999032480-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1999-07-01 | — | — | WO | disclosed |