Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 18/20 | 0.71 |
| ▸ | CTRC | Q99895 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356585 | 0.87 | CMA1 (0.56) | CMA1CTRCMAPK1REN | |
| SCHEMBL7348141 | 0.85 | MAPK1 (0.61) | CMA1CTRCMAPK1 | |
| SCHEMBL6695505 | 0.82 | CMA1 (1.00) | CMA1CTRC | |
| SCHEMBL6695507 | 0.82 | CMA1 (1.00) | CMA1CTRC | |
| SCHEMBL20174030 | 0.81 | ACE (0.67) | CMA1MAPK1REN | |
| SCHEMBL7348799 | 0.81 | MAPK1 (0.55) | CMA1MAPK1REN | |
| SCHEMBL7348789 | 0.81 | MAPK1 (0.55) | CMA1MAPK1REN | |
| SCHEMBL20174121 | 0.79 | F2 (0.54) | CMA1MAPK1REN | |
| SCHEMBL30487462 | 0.79 | MAPK1 (0.59) | CMA1MAPK1REN | |
| SCHEMBL7352708 | 0.79 | F2 (0.61) | CMA1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025574-A1 | INHIBITORS OF ANGIOTENSIN I CHYMASE(S) INCLUDING HUMAN HEART CHYMASE | PFIZER INC. (US) | 1993-12-23 | — | — | WO | disclosed |