Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 11/20 | 0.51 |
| ▸ | REN | P00797 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22962350 | 0.89 | F2 (0.57) | F2PRSS1CMA1 | |
| SCHEMBL20173781 | 0.89 | ITGB3 (0.47) | F2PRSS1MAPK1CMA1 | |
| SCHEMBL20174122 | 0.87 | OPRK1 (0.61) | F2OPRK1REN | |
| SCHEMBL22962154 | 0.85 | F2 (0.54) | F2PRSS1CMA1 | |
| SCHEMBL20173727 | 0.85 | OPRM1 (0.54) | F2PRSS1OPRK1CMA1REN | |
| SCHEMBL20174030 | 0.84 | ACE (0.67) | F2PRSS1MAPK1CMA1REN | |
| SCHEMBL22962005 | 0.84 | F2 (0.58) | F2PRSS1CMA1REN | |
| SCHEMBL30440351 | 0.83 | CMA1 (0.55) | F2PRSS1CMA1REN | |
| SCHEMBL20173734 | 0.83 | OPRM1 (0.54) | F2PRSS1OPRK1REN | |
| SCHEMBL7348141 | 0.82 | MAPK1 (0.61) | F2PRSS1MAPK1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094335-A1 | FINE-TUNE MODULATORS OF NEURONAL EXCITABILITY FOR NEUROPSYCHIATRIC DISORDERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-05-24 | — | — | WO | disclosed |