Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414428 | 0.82 | HTR1D (0.41) | HTR1DHTR1BLMNATP53MAPT | |
| SCHEMBL7407819 | 0.78 | KMT2A (0.44) | HTR6HTR1DHTR1BNR1H2NR1H3 | |
| SCHEMBL7415811 | 0.74 | HTR1B (0.50) | HTR1DHTR1BLMNATHRBEGFR | |
| SCHEMBL7410152 | 0.72 | HTR1D (0.50) | HTR1DHTR1BEGFRIGF1RFLT4 | |
| SCHEMBL7413807 | 0.69 | KMT2A (0.46) | HTR6HTR1DHTR1BMAPT | |
| SCHEMBL7407748 | 0.69 | HTR1D (0.51) | HTR6HTR1DHTR1BACHE | |
| Hydrochloric Acid SCHEMBL7406268 | 0.68 | HTR1D (0.50) | HTR6HTR1DHTR1BACHEEGFR | |
| SCHEMBL7410787 | 0.68 | HTR2A (0.47) | HTR6LMNATP53MAPTNR1H2 | |
| SCHEMBL7657062 | 0.67 | EGFR (0.51) | HTR1DHTR1BEGFRIGF1RFLT4 | |
| SCHEMBL7413500 | 0.67 | SIRT1 (0.50) | HTR6HTR1DHTR1BNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |