Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 5/20 | 0.50 |
| ▸ | HTR1D | P28221 | 4/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412246 | 0.88 | HTR1B (0.53) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL7409510 | 0.86 | SIRT1 (0.55) | HTR1BHTR1DSIRT1KMT2AMEN1 | |
| SCHEMBL7410152 | 0.85 | HTR1D (0.50) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL11730607 | 0.84 | SIRT1 (0.45) | HTR1BHTR1DSIRT1KMT2AMEN1 | |
| SCHEMBL4288837 | 0.82 | HTR1D (0.72) | HTR1BHTR1DKDRSIRT1KMT2A | |
| SCHEMBL7412220 | 0.79 | KMT2A (0.60) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL7407819 | 0.79 | KMT2A (0.44) | HTR1BHTR1DSIRT1KMT2AMEN1 | |
| SCHEMBL7412705 | 0.75 | L3MBTL1 (0.51) | HTR1BHTR1DSIRT1KMT2AMEN1 | |
| SCHEMBL7409267 | 0.74 | HTR6 (0.41) | HTR1BHTR1DEGFRIGF1RFLT4 | |
| SCHEMBL7407748 | 0.74 | HTR1D (0.51) | HTR1BHTR1DKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |