SCHEMBL5148367

SCHEMBL5148367

c1ccc(-c2ccc(-c3ncc[nH]3)cc2)cc1

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.91
MTOR P42345 1/20 0.91
ADK P55263 1/20 0.91
ALDH1A1 P00352 3/20 0.61
KDM4E B2RXH2 2/20 0.61
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP19A1 P11511 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
PDE3B Q13370 1/20 0.50
PDE3A Q14432 1/20 0.50
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
VCP P55072 2/20 0.43
CSNK1A1 P48729 1/20 0.43
TYRO3 Q06418 1/20 0.43
DYRK1B Q9Y463 1/20 0.43
ADRA2A P08913 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7409338 0.98 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL9719773 0.96 NISCH (1.00) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL8901 0.96 NISCH (1.00) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL8898735 0.93 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL1881537 0.93 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL31511436 0.93 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL5796856 0.93 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL1954238 0.93 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL11072040 0.93 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL28283863 0.93 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114891230-B Functionalized MOF material, preparation method and application thereof as solid phase extraction adsorbent 山东省分析测试中心 2023-06-13 CN claimed
CN-114891230-A Functionalized MOF material, preparation method and application of functionalized MOF material as solid-phase extraction adsorbent 山东省分析测试中心 2022-08-12 CN claimed
CN-117482548-A Production device and process for synthesizing aldehyde through hydroformylation of olefin 万华化学集团股份有限公司 2024-02-02 CN disclosed
CN-117362675-A Preparation of cobalt-based metal organic framework material and application of cobalt-based metal organic framework material in resolution of cis-trans isomer of 1, 4-cyclohexanedicarboxylic acid 北京工业大学 2024-01-09 CN disclosed
CN-114891230-B Functionalized MOF material, preparation method and application thereof as solid phase extraction adsorbent 山东省分析测试中心 2023-06-13 CN disclosed
CN-114891230-A Functionalized MOF material, preparation method and application of functionalized MOF material as solid-phase extraction adsorbent 山东省分析测试中心 2022-08-12 CN disclosed
CN-111689946-A Carbazole aromatic ring thermal activation delayed fluorescent material and organic electroluminescent device thereof 深圳大学 2020-09-22 CN disclosed
US-9169282-B2 Metal complexes MERCK PATENT GMBH (DE) 2015-10-27 US disclosed
US-9169282-B2 Metal complexes MERCK PATENT GMBH (DE) 2015-10-27 US disclosed
US-20110284799-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
US-20110284799-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
WO-2010086089-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2010-08-05 WO disclosed
CN-101267809-A Sugar coatings and methods therefor WYETH CORP (US) 2008-09-17 CN disclosed
EP-1861387-A1 NOVEL BENZOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2007-12-05 EP disclosed
WO-2006080821-A1 NOVEL BENZOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2006-08-03 WO disclosed
EP-1257551-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS PARP INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 2002-11-20 EP disclosed
WO-2001057038-A9 HETEROCYCLIC COMPOUNDS AND THEIR USE AS PARP INHIBITORS BASF AG (DE) 2001-09-20 WO disclosed
WO-2001057038-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS PARP INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 2001-08-09 WO disclosed
CN-1265033-A Certain diarylimidaozle derivatives, new class of NPY speific ligands NEUROGEN CORP (US) 2000-08-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110284799-A1 METAL COMPLEXES SOD1, AP1M1, AP3M1 NISCH 1434/4885MTOR 4584/4885ADK 4286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.