Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409613 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MAPTSMN1; SMN2GPR132TP53 | |
| SCHEMBL7382735 | 0.95 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2GPR132TP53 | |
| SCHEMBL7375604 | 0.92 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2GPR132LMNA | |
| SCHEMBL7375609 | 0.92 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2GPR132LMNA | |
| SCHEMBL7382275 | 0.91 | NR1H4 (0.38) | ALDH1A1GPR132CA12CA1CA2 | |
| SCHEMBL7382280 | 0.91 | NR1H4 (0.38) | ALDH1A1GPR132CA12CA1CA2 | |
| SCHEMBL7466505 | 0.89 | ITGB3 (0.40) | ALDH1A1MAPTSMN1; SMN2GPR132NPC1 | |
| SCHEMBL7466500 | 0.89 | ITGB3 (0.40) | ALDH1A1MAPTSMN1; SMN2GPR132NPC1 | |
| SCHEMBL7410389 | 0.89 | ITGB3 (0.40) | ALDH1A1MAPTGPR132 | |
| SCHEMBL7410561 | 0.89 | ITGB3 (0.40) | ALDH1A1MAPTGPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |