Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410561 | 1.00 | ITGB3 (0.40) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7408428 | 0.92 | MAPT (0.37) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7375609 | 0.91 | ALDH1A1 (0.39) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7375604 | 0.91 | ALDH1A1 (0.39) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7466505 | 0.89 | ITGB3 (0.40) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7466500 | 0.89 | ITGB3 (0.40) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7409609 | 0.89 | ALDH1A1 (0.38) | GPR132ALDH1A1MAPT | |
| SCHEMBL7409613 | 0.89 | ALDH1A1 (0.38) | GPR132ALDH1A1MAPT | |
| SCHEMBL7382275 | 0.87 | NR1H4 (0.38) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL7382280 | 0.87 | NR1H4 (0.38) | ITGB3ITGB1ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |