Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 15/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403509 | 0.88 | F10 (0.67) | F10PRSS1 | |
| SCHEMBL7401213 | 0.83 | F10 (0.40) | F10PRSS1 | |
| SCHEMBL7084793 | 0.80 | F10 (0.41) | F10PRSS1 | |
| SCHEMBL7056535 | 0.77 | PRSS1 (0.42) | F10PRSS1 | |
| SCHEMBL6993750 | 0.76 | FPR2 (0.42) | F10USP30PRSS1 | |
| SCHEMBL6995330 | 0.76 | F10 (0.42) | F10USP30PRSS1 | |
| SCHEMBL7076640 | 0.75 | F10 (0.41) | F10PRSS1 | |
| SCHEMBL7409027 | 0.75 | F10 (0.60) | F10PRSS1 | |
| SCHEMBL6375140 | 0.75 | USP30 (0.56) | F10USP30 | |
| SCHEMBL6381183 | 0.75 | USP30 (0.56) | F10USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030880-A2 | N-SUBSTITUTED AMINO ACID DERIVATIVES (FACTOR XA INHIBITORS) | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | claimed |
| WO-2002030880-A2 | N-SUBSTITUTED AMINO ACID DERIVATIVES (FACTOR XA INHIBITORS) | MERCK PATENT GMBH (DE) | 2002-04-18 | — | — | WO | disclosed |