Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403547 | 0.88 | TSHR (0.46) | HTR1FTSHRKDM4EMAPK1HSD17B10 | |
| SCHEMBL7413318 | 0.84 | CHRM3 (0.45) | HTR1FKMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL7409574 | 0.83 | ALDH1A1 (0.45) | HTR1FTSHRMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL7407346 | 0.82 | ALDH1A1 (0.44) | HTR1FTSHRKDM4ECYP1A2CYP2D6 | |
| SCHEMBL7411269 | 0.81 | HTR1F (0.36) | HTR1FTSHRMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7414478 | 0.81 | HTR1F (0.35) | HTR1FTSHRMEN1NPC1RAB9A | |
| SCHEMBL7412749 | 0.79 | HTR1F (0.41) | HTR1FCHRM3HSD17B10CHRM2CHRM1 | |
| SCHEMBL9189965 | 0.78 | CHRM3 (0.56) | CHRM3CHRM2CHRM1 | |
| SCHEMBL7410925 | 0.78 | CHRM3 (0.43) | HTR1FCHRM3CHRM2CHRM1 | |
| SCHEMBL7409636 | 0.77 | KMT2A (0.65) | HTR1FMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |