Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7407346 | 0.99 | ALDH1A1 (0.44) | ALDH1A1CLEC4MGFERHTR1FALOX15 | |
| SCHEMBL7417232 | 0.88 | BRD4 (0.41) | ALDH1A1GFERHTR1FALOX15MAPK1 | |
| SCHEMBL7417151 | 0.85 | HTR1F (0.47) | GFERHTR1FALOX15MAPK1CASP1 | |
| SCHEMBL7409117 | 0.84 | GFER (0.59) | GFERHTR1FALOX15MAPK1CASP1 | |
| SCHEMBL7410680 | 0.83 | ALOX15 (0.60) | ALDH1A1GFERHTR1FALOX15MAPK1 | |
| Water SCHEMBL7414567 | 0.83 | GFER (0.57) | GFERHTR1FALOX15MAPK1CASP1 | |
| SCHEMBL7413250 | 0.83 | GFER (0.45) | GFERHTR1FALOX15MAPK1CASP1 | |
| SCHEMBL7410084 | 0.83 | HTR1F (0.41) | HTR1FMAPK1HSD17B10TSHR | |
| SCHEMBL7407705 | 0.82 | CHRM2 (0.39) | ALDH1A1GFERHTR1FALOX15MAPK1 | |
| SCHEMBL7412952 | 0.82 | RAB9A (0.45) | ALDH1A1GFERALOX15MAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |