Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 12/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | C1S | P09871 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689035 | 0.85 | PARP1 (0.55) | — | |
| SCHEMBL171243 | 0.79 | RAB9A (0.55) | ALDH1A1 | |
| SCHEMBL7440442 | 0.79 | PRSS1 (0.57) | PRSS1PRSS2PRSS3F2ALDH1A1 | |
| SCHEMBL9335857 | 0.78 | UNG (0.45) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL3901564 | 0.78 | KMT2A (0.60) | ALDH1A1 | |
| Amicarbalide SCHEMBL1818799 | 0.78 | PLAU (0.65) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL11041250 | 0.78 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL12129057 | 0.77 | ALDH1A1 (0.67) | ALDH1A1 | |
| SCHEMBL10671451 | 0.77 | PRSS1 (0.52) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL10177622 | 0.77 | PRSS1 (0.52) | PRSS1PRSS2PRSS3F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542708-B1 | Substituted beta-amino acid derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-1993007867-A1 | SUBSTITUTED β-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-04-29 | — | — | WO | disclosed |