Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410052 | 0.93 | DRD2 (0.65) | DRD2DRD3HTR6CHRM2HTR1A | |
| SCHEMBL7412035 | 0.89 | HTR6 (0.55) | DRD2DRD3HTR6CHRM2HTR1A | |
| SCHEMBL7411149 | 0.81 | HTR6 (0.66) | DRD2DRD3HTR6CHRM2HTR1A | |
| SCHEMBL7410827 | 0.79 | PTGDR2 (0.54) | DRD2DRD3HTR6CHRM2HTR1A | |
| SCHEMBL7413011 | 0.78 | PTGDR2 (0.46) | DRD2DRD3HTR6CHRM2HTR1A | |
| SCHEMBL7406719 | 0.78 | HTR2A (0.53) | DRD2DRD3HTR6HTR2AHTR2C | |
| SCHEMBL7411294 | 0.78 | DRD3 (0.58) | DRD2DRD3HTR6CHRM2HTR1A | |
| SCHEMBL25818911 | 0.78 | HTR6 (0.85) | DRD2DRD3HTR6CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL7452433 | 0.78 | PTGDR2 (0.45) | DRD2DRD3HTR6CHRM2HTR1A | |
| SCHEMBL7410597 | 0.76 | HTR6 (0.57) | DRD2DRD3HTR6CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |