Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.48 |
| ▸ | NPC1 | O15118 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | APP | P05067 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ILK | Q13418 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948833 | 0.77 | RAB9A (0.43) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL29392710 | 0.74 | PI4KA (0.58) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL75245 | 0.74 | PI4KA (0.58) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL706413 | 0.72 | ILK (0.46) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL7902646 | 0.72 | RAB9A (0.40) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| Water SCHEMBL4365800 | 0.72 | PI4KA (0.56) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9229829 | 0.72 | PI4KA (0.56) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| Hydrogen Sulfide SCHEMBL11608879 | 0.72 | PI4KA (0.56) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL9559770 | 0.72 | PI4KA (0.56) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| Water SCHEMBL28456701 | 0.72 | PI4KA (0.56) | RAB9ANPC1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900088-A2 | INCLUSION COMPLEXES OF ARYL-HETEROCYCLIC SALTS | PFIZER INC. (US) | 1999-03-10 | — | — | EP | claimed |
| WO-1997041896-A2 | INCLUSION COMPLEXES OF ARYL-HETEROCYCLIC SALTS | PFIZER INC. (US) | 1997-11-13 | — | — | WO | claimed |